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Search Results for " serine protease 5 "
Targets Recommended: Serine Protease

2

抑制剂 & 化合物

13

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TP1792L KKI-5 acetate(97145-43-2 free base)

Serine Protease Proteases/Proteasome
KKI-5 acetate(97145-43-2 free base) 是一种丝氨酸蛋白酶抑制剂,可抑制激肽释放酶和纤溶酶。 KKI 5 可能表现出抗癌化疗益处,也可用作血管性水肿的治疗方法。
TP1792 KKI-5

KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.

化合物

KKI-5 acetate(97145-43-2 free base)
Cat.No: TP1792L
Synonym:
Target: Serine Protease
KKI-5
Cat.No: TP1792
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-01203 HATL5 Protein, Human, Recombinant (His)

HATL5,Transmembrane Protease Serine

Human HEK293 Cells
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease that may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
TMPJ-01069 Serpin A1e Protein, Mouse, Recombinant (His)

Dom5,α-1-antitrypsin 1-5,Serpina1e,Spi1-

Mouse HEK293 Cells
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein ...
TMPJ-00980 Complement Factor MASP3 Protein, Human, Recombinant (His)

PRSS5,CRARF,Serine Protease 5...

Human HEK293 Cells
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2...
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His)

Plasminogen Activator Inhibitor 3,Acrosomal Serine ...

Human HEK293 Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...
TMPY-00323 Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)

NS3

HCV E. coli
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His)

GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc)

SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC

Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc)

GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...

Human HEK293 Cells
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A

Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854 ETS1 Protein, Human, Recombinant (His)

V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...

Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...

Human HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

HATL5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01203
Species: Human
Expression System: HEK293 Cells
Serpin A1e Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01069
Species: Mouse
Expression System: HEK293 Cells
Complement Factor MASP3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00980
Species: Human
Expression System: HEK293 Cells
Serpin A5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00490
Species: Human
Expression System: HEK293 Cells
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
Cat.No: TMPY-00323
Species: HCV
Expression System: E. coli
CD45 Protein, Human, Recombinant (aa 1-529, His)
Cat.No: TMPY-05308
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05387
Species: Human
Expression System: HEK293 Cells
GRIK2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04318
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05547
Species: Human
Expression System: HEK293 Cells
ETS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00854
Species: Human
Expression System: E. coli
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05498
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01357
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01363
Species: Human
Expression System: HEK293 Cells
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