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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1792L |
KKI-5 acetate(97145-43-2 free base)
|
Serine Protease | Proteases/Proteasome |
KKI-5 acetate(97145-43-2 free base) 是一种丝氨酸蛋白酶抑制剂,可抑制激肽释放酶和纤溶酶。 KKI 5 可能表现出抗癌化疗益处,也可用作血管性水肿的治疗方法。 | |||
TP1792 |
KKI-5
|
||
KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01203 |
HATL5 Protein, Human, Recombinant (His)
HATL5,Transmembrane Protease Serine |
Human | HEK293 Cells |
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease that may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. | |||
TMPJ-01069 |
Serpin A1e Protein, Mouse, Recombinant (His)
Dom5,α-1-antitrypsin 1-5,Serpina1e,Spi1- |
Mouse | HEK293 Cells |
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein ... | |||
TMPJ-00980 |
Complement Factor MASP3 Protein, Human, Recombinant (His)
PRSS5,CRARF,Serine Protease 5... |
Human | HEK293 Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2... | |||
TMPJ-00490 |
Serpin A5 Protein, Human, Recombinant (His)
Plasminogen Activator Inhibitor 3,Acrosomal Serine ... |
Human | HEK293 Cells |
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o... | |||
TMPY-00323 |
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
NS3 |
HCV | E. coli |
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t... | |||
TMPY-05308 |
CD45 Protein, Human, Recombinant (aa 1-529, His)
GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPY-05387 |
SLAMF7 Protein, Human, Recombinant (hFc)
SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-04318 |
GRIK2 Protein, Human, Recombinant (hFc)
GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate... |
Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl... | |||
TMPY-05547 |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A |
Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPJ-00854 |
ETS1 Protein, Human, Recombinant (His)
V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),... |
Human | E. coli |
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As... | |||
TMPY-05498 |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas... |
Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5. | |||
TMPK-01357 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. | |||
TMPK-01363 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... |